Recombinant Human MIP-4 (CCL18) | Z100715

abm | Recombinant Human MIP-4 (CCL18) | Z100715

CCL18, also designated dendritic cell (DC)3-derived CC chemokine 1, pulmonary and activation-regulated chemokine, alternative macrophage activation-associated CC chemokine 1, and MIP-4, is a human chemokine structurally related to CCL3. CCL18 was shown to be expressed in germinal centers of tonsils by dendritic cells and to attract mainly naive T cells, CD38 mantle zone B lymphocytes and DC. The production of CCL18 by APC is enhanced by Th2 cytokines like IL-4 and IL-13 and suppressed by IFN-gamma.

Functions:

Determined by its ability to chemoattract human T cells using a concentration range of 2-40 ng/mL.

Organism:

Human

Source:

E. coli

Alias:

MIP4, CCL18, Pulmonary and activation-regulated chemokine, PARC, DC-CK1, AMAC-1, C-C motif chemokine 18, Small-inducible cytokine A18
Recombinant Human Macrophage Inflammatory Protein-4 (CCL18)

Gene Symbol:

CCL18

Gene ID:

6362

Accession:

P55774

Formulation:

Recombinant CC18 was lyophilized from a 0.2 μm filtered 20 mM PB,100 mM NaCl solution pH 7.5.

Solubility:

A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers.

Appearance:

Lyophilized Powder

Molecular Weight (kDa):

8

Molecular Weight 2 (kDA):

N/A

Molecular Weight 3 (kDA):

N/A

Purity:

>95% as determined by SDS-PAGE

Concentration:

<1.0 EU/μg of recombinant protein as determined by the LAL method.

Shipping Condition :

Ambient Temperature

Storage Condition:

The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.