abm human recombinant protein
Recombinant Human MLK2 (N-GST tag) | Z500228
- SKU:
- Z500228
- Availability:
- 5 to 7 Days Shipment
Description
abm | Recombinant Human MLK2 (N-GST tag) | Z500228
MLK2 or mixed-lineage kinase 2 is a member of the serine/threonine kinase family, which activates MAPK8 JNK and MKK4/SEK1. MLK2 itself can be phoshorylated, and activated by JNK kinases. MLK2 is also known as mitogen-activated protein kinase kinase kinase 10 (MAP3K10). MLK2 functions preferentially on the JNK signaling pathway which is involved in nerve growth factor (NGF) induced neuronal apoptosis. MLK2 was isolated as a cDNA fragment from MKN28 gastric cancer cell library using degenerate PCR . MLK2 is highly expressed in brain, skeletal muscle, and testis .
Functions:
The specific activity of MLK2 was determined to be 48 nmol /min/mg as per activity assay protocol.
Organism:
Human
Source:
Insect cells
Alias:
MAP3K10, MST
Gene Symbol:
MLK2
Gene ID:
N/A
Accession:
NM_002446
Formulation:
50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
Solubility:
N/A
Appearance:
Liquid
Molecular Weight (kDa):
76
Molecular Weight 2 (kDA):
N/A
Molecular Weight 3 (kDA):
N/A
Purity:
70% - 90%
Concentration:
Shipping Condition :
Dry Ice
Storage Condition:
Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.