Recombinant Human MYO3alpha (N-GST tag) | Z500245

abm | Recombinant Human MYO3alpha (N-GST tag) | Z500245

MYO3alpha belongs to the myosin superfamily which are members of the large myosin superfamily and are categorized into conventional myosins (class II) and unconventional myosins (classes I and III through XV) based on their variable C-terminal cargo-binding domains. Class III myosins, such as MYO3alpha, have a kinase domain N-terminal to the conserved N-terminal motor domains and are expressed in photoreceptors . MYO3alpha plays an important role in hearing in humans and mutations in the MYO3alpha have been shown to cause nonsyndromic progressive hearing loss . MYO3alpha is highly expreesed in retina and cochlea.

Functions:

The specific activity of MYO3awas determined to be 4 nmol /min/mg as per activity assay protocol.

Organism:

Human

Source:

Insect cells

Alias:

myosin IIIA; DFNB30

Gene Symbol:

MYO3a

Gene ID:

N/A

Accession:

NM_017433

Formulation:

50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.

Solubility:

N/A

Appearance:

Liquid

Molecular Weight (kDa):

76

Molecular Weight 2 (kDA):

N/A

Molecular Weight 3 (kDA):

N/A

Purity:

70% - 90%

Concentration:

Shipping Condition :

Dry Ice

Storage Condition:

Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.