Recombinant Human PDGFR alpha (N-GST tag) | Z500277

abm | Recombinant Human PDGFR alpha (N-GST tag) | Z500277

PDGFRa (platelet-derived growth factor receptor a) is a member of the PDGFR family of membrane receptors with intrinsic tyrosine kinase activity. Aberrant expression of PDGFRa has been linked to developmental abnormalities in vertebrate models and has been implicated in multiple disease states in humans. There is widespread expression of PDGFRa in renal cell types involved in fibrotic and sclerosing processes . PDGF and its receptor PDGFRa are inducers of fibrosis in the repair phase of inflammatory bowel disease and they may also be involved in the active inflammatory phase .

Functions:

The specific activity of PDGFRa was determined to be 12 nmol /min/mg as per activity assay protocol.

Organism:

Human

Source:

Insect cells

Alias:

CD140A, PDGFR2, MGC74795, Rhe-PDGFRA

Gene Symbol:

PDGFRa

Gene ID:

N/A

Accession:

NM_006206

Formulation:

50mM Tris-HCl, pH 7.5, 150mM NaCl, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, 25% glycerol.

Solubility:

N/A

Appearance:

Liquid

Molecular Weight (kDa):

95

Molecular Weight 2 (kDA):

N/A

Molecular Weight 3 (kDA):

N/A

Purity:

70% - 90%

Concentration:

Shipping Condition :

Dry Ice

Storage Condition:

Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.