Recombinant Mouse PDGFR alpha (N-GST tag) | Z600020

abm | Recombinant Mouse PDGFR alpha (N-GST tag) | Z600020

PDGFRa (platelet-derived growth factor receptor A) is a member of the PDGFR family of membrane receptors with intrinsic tyrosine kinase activity. Aberrant expression of PDGFRa has been linked to developmental abnormalities in vertebrate models and has been implicated in multiple disease states in humans. There is widespread expression of PDGFRa in renal cell types involved in fibrotic and sclerosing processes. PDGF and its receptor PDGFRa are inducers of fibrosis in the repair phase of inflammatory bowel disease and they may also be involved in the active inflammatory phase .

Functions:

The specific activity of PDGFRa was determined to be 14 nmol /min/mg as per activity assay protocol.

Organism:

Mouse

Source:

Insect cells

Alias:

CD140a; Pdgfr-2; AI115593

Gene Symbol:

PDGFRa

Gene ID:

N/A

Accession:

NM_011058

Formulation:

50mM Tris-HCl, pH 7.5, 150mM NaCl, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, 25% glycerol.

Solubility:

N/A

Appearance:

Liquid

Molecular Weight (kDa):

100

Molecular Weight 2 (kDA):

N/A

Molecular Weight 3 (kDA):

N/A

Purity:

70% - 90%

Concentration:

Shipping Condition :

Dry Ice

Storage Condition:

Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.