abm human recombinant protein
Recombinant Human PI3K (p110 alpha/p55 gamma) (N-His tag) | Z500288
- SKU:
- Z500288
- Availability:
- 5 to 7 Days Shipment
Description
abm | Recombinant Human PI3K (p110 alpha/p55 gamma) (N-His tag) | Z500288
PI3K (p110alpha/p55gamma) or Phosphatidylinositol 3-kinase is a lipid kinase that phosphorylates the inositol ring of phosphatidylinositol at the 3-prime position which serve as second messengers in growth signaling pathways. PI3K comprises a 110 kD catalytic subunit and a regulatory subunit of either 85, 55, or 50 kD. Phosphatidylinositol 3-kinase plays an important role in the metabolic actions of insulin, and a mutation in the PI3K has been associated with insulin resistance and plays an important role in glucose homeostasis in vivo . PI3K also plays an essential role in the development and induction of mast cells in normal and pathogenic immune responses .
Functions:
The specific activity of PI3K(p110a/p55?)wasdetermined to be 14 nmol /min/mg as per activity assay protocol.
Organism:
Human
Source:
Insect cells
Alias:
p110a: PI3K, p110-alpha p55g: PIK3R3, p55, p55-GAMMA, FLJ41892
Gene Symbol:
PI3K (p110a/p55?)
Gene ID:
N/A
Accession:
NM_006218, BC021622
Formulation:
50mM sodium, pHosphate, pH 7.0, 300mM NaCl, 150mM imidazole, 0.1mM PMSF, 0.25mM DTT, 25% glycerol.
Solubility:
N/A
Appearance:
Liquid
Molecular Weight (kDa):
111
Molecular Weight 2 (kDA):
61
Molecular Weight 3 (kDA):
N/A
Purity:
70% - 90%
Concentration:
Shipping Condition :
Dry Ice
Storage Condition:
Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.