Recombinant Human PIK3C3 (Vps34) (N-GST tag) | Z500299

abm | Recombinant Human PIK3C3 (Vps34) (N-GST tag) | Z500299

PIK3C3 or phosphoinositide-3-kinase is a member of the PI 3-kinase family that mediates the active diversion of proteins from the secretory pathway to vacuoles. PIK3C3 are involved in both receptor-mediated signal transduction and intracellular trafficking. In yeast, the vps34 gene product is a PI 3-kinase. PIK3C3 has a substrate specificity and ion requirements that are distinct from the other known mammalian PI 3-kinases . PIK3C3 mediate catalysis on membranes and suppress futile adenosine triphosphatase cycles. PIK3C3 appears to alternate between a closed cytosolic form and an open form on the membrane .

Functions:

The specific activity of PIK3C3 was determined to be 98 nmol /min/mg as per activity assay protocol

Organism:

Human

Source:

Insect cells

Alias:

VPS34, hVps34, MGC61518

Gene Symbol:

PIK3C3 (Vps34)

Gene ID:

N/A

Accession:

NM_002647

Formulation:

50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.

Solubility:

N/A

Appearance:

Liquid

Molecular Weight (kDa):

128

Molecular Weight 2 (kDA):

N/A

Molecular Weight 3 (kDA):

N/A

Purity:

70% - 90%

Concentration:

Shipping Condition :

Dry Ice

Storage Condition:

Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.