Recombinant Human PKC alpha (N-GST tag) | Z500310

abm | Recombinant Human PKC alpha (N-GST tag) | Z500310

PKCa is a member of the protein kinase C (PKC) family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC-alpha has been reported to play roles in many different cellular processes, such as cell adhesion, cell transformation, cell cycle checkpoint, and cell volume control. PKCa has been assigned to the chromosome region 17q22-q23.2 and has been identified as a fundamental regulator of cardiac contractility and Ca(2+) handling in myocytes .

Functions:

The specific activity of PKCa was determined to be 2900nmol/min/mg as per activity assay protocol

Organism:

Human

Source:

Insect cells

Alias:

AAG6, PKCA, PRKCA, PRKACA, MGC129900, MGC129901

Gene Symbol:

PKCa

Gene ID:

N/A

Accession:

NM_002737

Formulation:

50mM Tris-HCl, pH 7.5, 150mM NaCl, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, 25% glycerol.

Solubility:

N/A

Appearance:

Liquid

Molecular Weight (kDa):

103

Molecular Weight 2 (kDA):

N/A

Molecular Weight 3 (kDA):

N/A

Purity:

70% - 90%

Concentration:

Shipping Condition :

Dry Ice

Storage Condition:

Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.