Recombinant Human PKC zeta (N-GST tag) | Z500321

abm | Recombinant Human PKC zeta (N-GST tag) | Z500321

PKC? is an atypical isoform of the PKC family. PKC? is found in both particulate and soluble fractions and cannot be activated by phorbol ester. Overexpression of PKC? and subsequent phorbol ester treatment abolished phorbol ester-induced reduction in cell proliferation . Overexpression of PKC? also potentiates phorbol ester-induced mitogen-activated protein (MAP) kinase activation in a PKC-dependent manner. PKC? is an upstream modulator of p70S6K, an important regulator of cell proliferation .

Functions:

The specific activity of PKC? was determined to be 130 nmol /min/mg as per activity assay protocol

Organism:

Human

Source:

Insect cells

Alias:

PRKCZ; PRKCZ; PKC2

Gene Symbol:

PKC?

Gene ID:

N/A

Accession:

NM_002744

Formulation:

50mM Tris-HCl, pH 7.5, 150mM NaCl, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, 25% glycerol.

Solubility:

N/A

Appearance:

Liquid

Molecular Weight (kDa):

93

Molecular Weight 2 (kDA):

N/A

Molecular Weight 3 (kDA):

N/A

Purity:

70% - 90%

Concentration:

Shipping Condition :

Dry Ice

Storage Condition:

Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.