Recombinant Human PKC epsilon (N-GST tag) | Z500314

abm | Recombinant Human PKC epsilon (N-GST tag) | Z500314

PKCe is a member of the protein kinase C (PKC) family of serine- and threonine-specific protein kinases that can phosphorylate a wide variety of protein targets known to be involved in diverse cellular signaling pathways. PKCe is involved in many different cellular functions, such as neuron channel activation , cardioprotection from ischemia , heat shock response, as well as insulin exocytosis. Knockout studies in mice suggest that this kinase is important for lipopolysaccharide (LPS)-mediated signaling in activated macrophages and may control anxiety-like behavior .

Functions:

The specific activity of PKCe was determined to be 1258 nmol /min/mg as per activity assay protocol

Organism:

Human

Source:

Insect cells

Alias:

PRKCE; MGC125656; MGC125657; nPKC-epsilon

Gene Symbol:

PKCe

Gene ID:

N/A

Accession:

NM_005400

Formulation:

50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.

Solubility:

N/A

Appearance:

Liquid

Molecular Weight (kDa):

110

Molecular Weight 2 (kDA):

N/A

Molecular Weight 3 (kDA):

N/A

Purity:

70% - 90%

Concentration:

Shipping Condition :

Dry Ice

Storage Condition:

Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.