Recombinant Human PKN1/PRK1 (N-GST tag) | Z500323

abm | Recombinant Human PKN1/PRK1 (N-GST tag) | Z500323

PKN1/PRK1 belongs to the protein kinase C superfamily which is activated by Rho family of small G proteins. PKN1/PRK1 is known to mediate the Rho-dependent signaling pathway and it can be activated by phospholipids and by limited proteolysis . PDPK1/PDK may also mediate insulin signals to the actin cytoskeleton and the proteolytic activation of this kinase by caspase-3 or related proteases during apoptosis suggest its role in signal transduction related to apoptosis. PKN1/PRK signaling stimulates AR activity in the presence of adrenal androgens and in the presence of an AR antagonist .

Functions:

The specific activity of PKN1/PRK1 was determined to be 30 nmol /min/mg as per activity assay protocol.

Organism:

Human

Source:

Insect cells

Alias:

PRK1, DBK, PKN1, PKN, MGC46204, PAK1, PRKCL1, PKC-L1

Gene Symbol:

PKN1/PRK1

Gene ID:

N/A

Accession:

BC040061

Formulation:

50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.

Solubility:

N/A

Appearance:

Liquid

Molecular Weight (kDa):

115

Molecular Weight 2 (kDA):

N/A

Molecular Weight 3 (kDA):

N/A

Purity:

70% - 90%

Concentration:

Shipping Condition :

Dry Ice

Storage Condition:

Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.