Recombinant Human SRC (N-GST tag) | Z500365

abm | Recombinant Human SRC (N-GST tag) | Z500365

SRC family belongs to non-receptor tyrosine kinases. SRC was originally identified as a transforming protein of the Rous sarcoma virus (RSV) that had enzymatic ability to phosphorylate tyrosine in protein substrates . SRC is overexpressed and activated in a large number of human malignancies and has been linked to the development of cancer and progression to distant metastases . In addition to increasing cell proliferation, a key role of SRC in cancer seems to be the ability to promote invasion and motility, functions that might contribute to tumour progression.

Functions:

The specific activity of SRC was determined to be 98 nmol /min/mg as per activity assay protocol.

Organism:

Human

Source:

Insect cells

Alias:

ASV; SRC1; c-SRC; p60-Src

Gene Symbol:

SRC

Gene ID:

N/A

Accession:

NM_005417

Formulation:

50mM Tris-HCl, pH 7.5, 150mM NaCl, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, 25% glycerol.

Solubility:

N/A

Appearance:

Liquid

Molecular Weight (kDa):

83

Molecular Weight 2 (kDA):

N/A

Molecular Weight 3 (kDA):

N/A

Purity:

70% - 90%

Concentration:

Shipping Condition :

Dry Ice

Storage Condition:

Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.