Recombinant Human Thymosin-Beta 4 (TMSB4X) | Z102009

abm | Recombinant Human Thymosin-Beta 4 (TMSB4X) | Z102009

The primary function of the T beta-4 member of the Thymosin-beta family is to maintain the organization of the cell’s cytoskeletal structure. Produced by myoblasts and fibroblasts, TMSB4X acts as a modulator for the production and digestion of actin and to inhibit filamentous actin polymerization. TMSB4X has also been found to induce phenotypic changes in T cell lines during early host defence mechanisms and inhibit the progression of hematopoietic pluripotent stem cells into the s-phase.

Functions:

The ED(50) was determined by the dose-dependent proliferation of immortalized mouse brain endothelial cells and was found to be <0.5ng/mL.

Organism:

Human

Source:

E. coli

Alias:

T beta-4, Hematopoietic system regulatory peptide, Seraspenide, TMSB4X, TB4X, TMSB4

Gene Symbol:

TMSB4X

Gene ID:

7114

Accession:

P62328

Formulation:

Lyophilized from a 0.2 μm filtered solution in PBS

Solubility:

Reconstitute at 100 μg/mL in sterile PBS

Appearance:

Lyophilized Powder

Molecular Weight (kDa):

5,2

Molecular Weight 2 (kDA):

N/A

Molecular Weight 3 (kDA):

N/A

Purity:

>95% as determined by SDS-PAGE

Concentration:

< 1.0 EU/μg of recombinant protein as determined by the LAL method.

Shipping Condition :

Ambient Temperature

Storage Condition:

The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.