abm human recombinant protein
Recombinant Human TXK (N-GST tag) | Z500399
- SKU:
- Z500399
- Availability:
- 5 to 7 Days Shipment
Description
abm | Recombinant Human TXK (N-GST tag) | Z500399
TXK or RLK is a member of the TEC family of non-receptor tyrosine kinases. TXK is expressed in T-cells and is an important component of signaling pathways downstream of lymphocyte antigen receptor. TXK is phosphorylated in response to T-cell receptor stimulation and can be activated by phosphorylation by Src family kinases. However, TXK is phosphorylated independent of PI-3K activity . Excessive TXK protein expression is seen in patients with Behcet's disease. Over production of TXK leads to increased Th1 cell function that is involved in the pathogenesis of Behcet’s disease .
Functions:
The specific activity of TXK was determined to be 18 nmol /min/mg as per activity assay protocol.
Organism:
Human
Source:
Insect cells
Alias:
RLK; TKL; BTKL; PTK4; PSCTK5; MGC22473
Gene Symbol:
TXK
Gene ID:
N/A
Accession:
NM_003328
Formulation:
50mM Tris-HCl, pH 7.5, 150mM NaCl, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, 25% glycerol.
Solubility:
N/A
Appearance:
Liquid
Molecular Weight (kDa):
53
Molecular Weight 2 (kDA):
N/A
Molecular Weight 3 (kDA):
N/A
Purity:
70% - 90%
Concentration:
Shipping Condition :
Dry Ice
Storage Condition:
Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.