Recombinant Mouse TGFBR2 (N-GST tag) | Z600026

abm | Recombinant Mouse TGFBR2 (N-GST tag) | Z600026

TGFBR2 is a member of the TGFbeta receptor subfamily and is a ser/thr protein kinase. TGFBR2-induced protein phosphorylation plays a key role in signal transduction that leads to mitogenic responses . The TGFBR2 receptor transmits signals from the cell surface to the nucleus and provides instructions for making transforming growth factor (TGF)-beta type II receptor. Mutations in TGFBR2 gene have been associated with Marfan Syndrome, Loeys-Deitz Aortic Aneurysm Syndrome, and the development of various types of tumors .

Functions:

The specific activity of TGFßR2 was determined to be 1.0 nmol /min/mgas per activity assay protocol

Organism:

Mouse

Source:

Insect cells

Alias:

1110020H15Rik; AU042018; DNIIR; RIIDN; TbetaR-II; TbetaRII; TBR-II

Gene Symbol:

TGFBR2

Gene ID:

N/A

Accession:

BC052629

Formulation:

50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.

Solubility:

N/A

Appearance:

Liquid

Molecular Weight (kDa):

69

Molecular Weight 2 (kDA):

N/A

Molecular Weight 3 (kDA):

N/A

Purity:

70% - 90%

Concentration:

Shipping Condition :

Dry Ice

Storage Condition:

Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.