Recombinant Human TGFBR2 (N-GST tag) | Z500386

abm | Recombinant Human TGFBR2 (N-GST tag) | Z500386

TGFßR2 is a member of the TGFß receptor subfamily and is a ser/thr protein kinase. TGFßR2-induced protein phosphorylation plays a key role in signal transduction that leads to mitogenic responses . The TGFßR2 receptor transmits signals from the cell surface to the nucleus and provides instructions for making transforming growth factor (TGF)-beta type II receptor. Mutations in TGFßR2 gene have been associated with Marfan Syndrome, Loeys-Deitz Aortic Aneurysm Syndrome, and the development of various types of tumors .

Functions:

The specific activity of TGFßR2 was determined to be 7 nmol /min/mg as per activity assay protocol.

Organism:

Human

Source:

Insect cells

Alias:

AAT3, FAA3, MFS2, RIIC, HNPCC6, TGFR-2, TGFbeta-RII, TAAD2

Gene Symbol:

TGFBR2

Gene ID:

N/A

Accession:

NM_003242

Formulation:

50mM Tris-HCl, pH 7.5, 150mM NaCl, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, 25% glycerol.

Solubility:

N/A

Appearance:

Liquid

Molecular Weight (kDa):

68

Molecular Weight 2 (kDA):

N/A

Molecular Weight 3 (kDA):

N/A

Purity:

70% - 90%

Concentration:

Shipping Condition :

Dry Ice

Storage Condition:

Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.