TrkA Stable T17 Cell Line | T3158
- 5 to 7 Days Shipment
abm | TrkA Stable T17 Cell Line | T3158
TrkA Stable T17 Cell Line expresses rat TrkA (Tropomyosin receptor kinase A) after TrkA plasmid was successfully transfected into SN56 cells and were selected in the presence of G418. TrkA is the receptor for neurotrophins, such as nerve growth factor (NGF), which plays essential role in the nervous system – in particular apoptotic cell death prevention, and/or the promotion of cellular differentiation and axon elongation in neurons. Researchers may use the TrkA Stable T17 Cell Line to screen for NGF-like compounds that would act as TrkA agonists to study the mechanisms of the signaling pathways and affects NGF. The lack of TrkA has been associated with the neurodegenerative processes and thus the cell line is a valuable tool to conduct related studies.
Thaw entire contents into an appropriate T25 flask as specified in the Propagation instructions.
For Research Use Only
Rat TrkA receptor via transfection and G418 antibiotic selection
The base medium for this cell line is Prigrow III medium available at abm
Selection with 300 mg/ml G418
10⁶ cells/1.0 ml