abm drug discovery

abm | CYP3A5 Double Deleted HuH-7 Cell Line | T6346Cells were derived from HuH-7 cells. Cells were then genetically modified using CRISPR/Cas9 method with two guide RNAs to homozygously delete...

abm | CYP3A5 Single Deleted HuH-7 Cell Line | T6347Cells were derived from HuH-7 cells. Cells were then genetically modified using CRISPR/Cas9 method with two guide RNAs to heterozygously delete...

abm | CYP3A5 Point Mutation HuH-7 Cell Line | T6348Cells were derived from HuH-7 cells. Cells were genetically modified using CRISPR/Cas9 method with 1 guide RNA and HDR template to heteroygously...

abm | IP6K1--- Stable HCT116 Cell Line | T6349To study the role that PP-IPs play in mammalian phosphate homeostasis, researchers generated cells devoid of this small molecule. CRISPR was used to...

abm | IP6K2--- Stable HCT116 Cell Line | T6350To study the role that PP-IPs play in mammalian phosphate homeostasis, researchers generated cells devoid of this small molecule. CRISPR was used to...

abm | IP6K1--- & IP6K2--- Stable HCT116 Cell Line | T6351To study the role that PP-IPs play in mammalian phosphate homeostasis, researchers generated cells devoid of this small molecule. CRISPR was...

abm | 3xFLAG-AGO2 Stable Expressing HEK293T Cell Line | T6352MicroRNAs (miRNAs) comprise a class of small non-coding RNAs that regulate the stability and/or translatability of most protein-coding...

abm | Prothrombin Mutant (R393Q) Stable Expressing HEK293 Cell Line | T6353Mannan-binding lectin-associated serine protease-1 (MASP-1) is a protein of the lectin pathway. Its similar in terms of...

abm | CHRFAM7A Stable Expressing PC12 Cell Line | T6354T6354 are rat PC12 cells which were stably transfected with human CHRFAM7A. CHRFAM7A is a uniquely-human gene that encodes a human-specific...

abm | Wildtype rFIX Stable Expressing HEK293 Cell Line | T6355Derived from HEK293 cells, Wildtype rFIX Stable Expressing HEK293 Cell Line was transfected to stably express human coagulation factor...

abm | Mutant rFIX Stable Expressing HEK293 Cell Line | T6356Derived from HEK293 cells, Mutant rFIX Stable Expressing HEK293 Cell Line was transfected to stably express the p.R294Q variant of human...

abm | LIMD1--- CRISPR Stable Knockout HeLa Cell Line | T6357LIMD1 knockout was conducted via CRISPR to establish the LIMD1-/- CRISPR Stable Knockout HeLa Cell Line. LIMD1 is an adapter or scaffold...