Recombinant Human FMS (N-GST tag) | Z500149

abm | Recombinant Human FMS (N-GST tag) | Z500149

FMS is a proto-oncogene that encodes the tyrosine kinase transmembrane receptor for colony stimulating factor 1 (CSF1). FMS is homodimeric that contains a so-called kinase insert domain and is a member of the CSF1/PDGF receptor family of tyrosine-protein kinases. FMS mediates most if not all of the biological effects of CSF1 which control the production, differentiation, and function of cell of the monocyte/macrophage lineage . Mutations in FMS have been associated with providing sustained signals for cell growth and a predisposition to myeloid malignancy .

Functions:

The specific activity of FMS was determined to be 24 nmol/min/mg as per activity assay protocol.

Organism:

Human

Source:

Insect cells

Alias:

CSF1R, CSFR, FIM2, C-FMS, CD115

Gene Symbol:

FMS

Gene ID:

N/A

Accession:

NM_005211

Formulation:

50mM Tris-HCl, pH 7.5, 150mM NaCl, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, 25% glycerol.

Solubility:

N/A

Appearance:

Liquid

Molecular Weight (kDa):

76

Molecular Weight 2 (kDA):

N/A

Molecular Weight 3 (kDA):

N/A

Purity:

70% - 90%

Concentration:

Shipping Condition :

Dry Ice

Storage Condition:

Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.