Recombinant Human Galectin-3 (LGALS3) | Z101825

abm | Recombinant Human Galectin-3 (LGALS3) | Z101825

Gal-3 interacts, via its lectin domain, with glycoproteins and glycolipids on the surface of animal cells. It has been shown that nuclear Gal­3 can modulate gene expression while cytosolic Gal­3 can inhibit apoptosis and participate in exocytosis. Gal-3 is generally expressed by the epithelial cells of many tissues as well as by inflammatory cells. An increased level of Gal-3 expression may lead to some lymphomas, as well as thyroid and hepatic carcinomas while the down-regulation has been associated with breast and colon cancer.

Functions:

Measured by its ability to agglutinate human red blood cells. The ED(50) for this effect is typically 3-10 µg/mL.

Organism:

Human

Source:

E. coli

Alias:

IgE-Binding Protein, Gal-3, 35 kDa lectin, Carbohydrate-binding protein 35, CBP 35, Galactose-specific lectin 3, Galactoside-binding protein, GALBP, L-31, Laminin-binding protein, Lectin L-29, Mac-2 antigen

Gene Symbol:

LGALS3

Gene ID:

3958

Accession:

P17931

Formulation:

Lyophilized from a 0.2 μm filtered solution in PBS.

Solubility:

Reconstitute at 50 μg/mL in sterile PBS containing at least 0.1% human or bovine serum albumin

Appearance:

Lyophilized Powder

Molecular Weight (kDa):

26,1

Molecular Weight 2 (kDA):

N/A

Molecular Weight 3 (kDA):

N/A

Purity:

>95% as determined by SDS-PAGE

Concentration:

< 1.0 EU/μg of recombinant protein as determined by the LAL method.

Shipping Condition :

Ambient Temperature

Storage Condition:

The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.