Recombinant Human NOV | Z102079

abm | Recombinant Human NOV | Z102079

Protein NOV homolog is a secreted, regulatory protein found mainly in muscle and nervous tissue which interacts with many molecules, including fibulin 1C, CCN2, Connexin43 (to regulate the suppression of cell proliferation) and S100A4 (trigger activation of calcium channels). By signalling through an integrin pathway, NovH promotes both cell migration and adhesion. Increased levels of NovH have been found in some tumour cells and in most nephroblastomas while decreased levels of this protein may also promote tumour growth.

Functions:

Measured by its ability to mediate Balb/3T3 mouse embryonic fibroblast cell adhesion

Organism:

Human

Source:

E. coli

Alias:

NovH, Insulin-Like Growth Factor-Binding Protein 9, CCN family member 3, IBP-9, IGF-binding protein 9, IGFBP-9, Nephroblastoma-overexpressed gene protein homolog
Recombinant Human Protein NOV homolog (NOV)

Gene Symbol:

NOV

Gene ID:

4856

Accession:

P48745

Formulation:

Lyophilized from a 0.2 μm filtered solution in PBS

Solubility:

Reconstitute at 250 μg/mL in sterile PBS

Appearance:

Lyophilized Powder

Molecular Weight (kDa):

36,5

Molecular Weight 2 (kDA):

N/A

Molecular Weight 3 (kDA):

N/A

Purity:

>95% as determined by SDS-PAGE

Concentration:

<1.0 EU/μg of recombinant protein as determined by the LAL method.

Shipping Condition :

Ambient Temperature

Storage Condition:

The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.