Recombinant Human TGFA | Z101935

abm | Recombinant Human TGFA | Z101935

An EGF family member, TGF-A is a cytokine that is produced following the protease digestion of its trans-membrane precursor proTGF-A. TGF-A is expressed both in normal tissues during embryogenesis and in adult tissues, such as the brain, keratinocytes, and macrophages and at high levels in transformed and tumour cells.

Functions:

Measured in a cell proliferation assay using Balb/3T3 mouse embryonic fibroblast cells. The ED(50) for this effect is typically 0.1­0.4 ng/mL.

Organism:

Human

Source:

E. coli

Alias:

TGF-alpha, TGF-A, isoform CRA_d
Recombinant Human Transforming Growth Factor Alpha (TGFA)

Gene Symbol:

TGFA

Gene ID:

7039

Accession:

P01135

Formulation:

Lyophilized from a 0.2 μm filtered solution in Acetonitrile and TFA

Solubility:

Reconstitute at 100 μg/mL in sterile 10 mM Acetic Acid

Appearance:

Lyophilized Powder

Molecular Weight (kDa):

5,8

Molecular Weight 2 (kDA):

N/A

Molecular Weight 3 (kDA):

N/A

Purity:

>95% as determined by SDS-PAGE

Concentration:

<1.0 EU/μg of recombinant protein as determined by the LAL method.

Shipping Condition :

Ambient Temperature

Storage Condition:

The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.