abm drug discovery
SIRT7 Stable Scramble H1299 Cell Line | T6259
- SKU:
- T6259
- Availability:
- 5 to 7 Days Shipment
Description
abm | SIRT7 Stable Scramble H1299 Cell Line | T6259
SIRT7 Stable Scramble H1299 Cell Line was generated by lentiviral driven expression of shRNAs. Lack of Sirt7 is associated with reduced recruitment of DNMT1 and Sirt1 at rRNA genes leading to hyperacetylation of histones, reduced DNA methylation, fragmentation of the nucleolar structure and loss of rDNA repeats.
Biosafety:
II
Organism:
Human
Source Organ:
Lung
Growth Properties:
Adherent
Morphology:
Epithelial-like
Clones:
N/A
Passage Number:
N/A
Population Doner:
22 - 32 hours
Seeding Density:
20,000 cells/cm2; Recommended split ratio of 1:2 to 1:4
Markers:
N/A
Applications:
For Research Use Only
Doner Gender:
N/A
Donor Ethnicity:
N/A
Knockdown Method:
N/A
Induction:
N/A
Overexpression:
N/A
Freeze Thaw:
N/A
Propagation:
The base medium for this cell line is Prigrow III medium available at abm
Preservation:
1. Freeze Medium: 90% FBS and 10% DMSO.
2. Storage Temperature: Liquid nitrogen vapour phase.
Quality Control:
N/A
Tumorgenicn:
N/A
Shipping Conditions:
Dry Ice
Storage Contidions:
-180°C